National Nanocenter JACS: Ultra obhityileyo CeO2 nano antioxidant

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Abantu bajonga i-oxide nanoenzymes njengezona zixhobo ezifanelekileyo zokulinganisa ukunyangwa kwe-oxidative stress-mediated pathophysiological disorders yi-antioxidant enzymes, kodwa umsebenzi we-catalytic we-oxide nanoenzymes awukaneliseki.

Ukujonga oku, uTang Zhiyong, uWang Hao, uXingxin Fa, uQiao Zengying, kunye nabanye abavela kwiZiko leNanometer yeSizwe baye baxela okokuqala ukuba i-ultra-thin layered.CeO2ngoxinzelelo lwangaphakathi lusetyenziselwa ukumelana ne-nano oxidation.
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Iingongoma eziphambili zeli nqaku

Ingongoma ephambili 1. Ngobalo lwethiyori kunye nohlalutyo, kwafunyaniswa ukuba uxinzelelo lomphezulu lweCeO2inxulumene nolungelelwaniso unsaturation ka Ce kunye nobunzimaCeO2. Ngako oko, i-ultra-thin nanosheets kunye nobukhulu be-~ 1.2 nm zenziwa, kwaye uxinzelelo lwe-in-plane / ngaphandle koxinzelelo lwendiza lwafikelela ~ 3.0% kunye ne-10.0%, ngokulandelanayo.

Inqaku eliphambili 2. Xa kuthelekiswa ne-nanocubes, le nanosheet ye-ultra-thin ye-Ce-O yekhemikhali ibhondi iye yaphucula i-covalence, ibangele ukwanda kwe-2.6 kwi-SOD efanisiweyo (i-superoxide dismutase) umsebenzi we-catalytic kunye nokunyuka kwe-2.5 ngokubanzi kwi-antioxidant umthamo. Ukusebenzisa le ultra-ebhityileyoCeO2ifilimu enoxinzelelo lwangaphakathi lokunyanga ischemic stroke in vivo inomsebenzi ongcono kunamachiza eklinikhi esintu
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Ixesha lokuposa: Sep-08-2023