Izifo eziNgezelelweyo zesifo (CKD) Izigulana zihlala zine-hyperphosphatia, kwaye i-hypernphosphatia yexesha elide ikhokelela kwiingxaki ezinkulu ezinje nge-hyperparathyyrofism, kunye nesifo sentliziyo. Ukulawulwa kwamanqanaba e-POPINIUS ye-phosphorous yinxalenye ebalulekileyo yolawulo lwezigulana ze-CKD, kwaye ii-photsphate ze-phosphate lingamachiza e-sesnesphosphatia. Kule minyaka yangoku,I-Lanthanum carbonate, njengohlobo olutsha lwe-non-calcium kunye ne-no-ialuminiya ye-phosphate ye-Binder, ngokuthe ngcembe yangena kwintsimi yabantu bombono yaza yaqalisa "ukhuphiswano" kunye ne-phosphate yemveli ye-phosphate.
"I-gorits" kunye "needemeri" ze-phoger yendabuko
Ii-photsphate zemveli zePisphate ikakhulu zibandakanya i-calcium-ene-pholcium ye-calcium ye-calcium kunye ne-calcium ye-calcium kunye ne-calcium ye-calcinute) kunye ne-aluminium hydroxide (njenge-aluminium hydroxide). Badibanisa ne-phosphates ekutyeni ukuze zenze amakhonkco angenalutho, ngaloo ndlela kuncitshiswa ukwamkelwa kwe-phosphorus.
I-calcium-ene-phosphate yee-phosphate ze-phosphate: ixabiso eliphantsi kunye ne-phosphorus eqinisekileyo, kodwa ukusetyenziswa kwexesha elide kunokukhokelela kwi-hypercalcemia kwaye kwandise umngcipheko wokubalwa kwe-vascular.
I-Aluminium-iqulethe i-phosphorus phosphorus: i-phosphorus yokuncitshiswa kwe-phosphorus, kodwa ukuqokelelwa kwe-alfarus kunetyhefu kwaye kunokubangela isifo sethambo le-aluminium kunye ne-Encephalopath, kwaye okwangoku kwaye okwangoku kwaye okwangoku kwaye okwangoku isetyenziswa.
I-Lanthanum Carbonate: Ukunyuka okutsha, kunye nezibonelelo ezibalulekileyo
I-Lanthanam Carbonate yi-carbinate ye-itant yomhlaba onqabileyo wensimbi, kunye ne-phosphorus ekhethekileyo ye-phosphorus. Ikhupha i-lantham i-ions kwindawo ye-acidic yephecana yokugaya kunye neefom kakhulu i-phospham phespham phospham e phosphate, ngaloo ndlela uthintela ukufunxa kwe phosphorus.
Ukwaziswa okufutshane kwe-lanthanum carbonate
| Igama lemveliso | I-Lanthanum carbonate |
| Ifomula | I-LA2 (CO3) 3.XH2O |
| I-CASS No. | I-64879 |
| Ubunzima bemolekyuli | I-457.85 (Anhy) |
| Ukuxinana | 2.6 g / cm3 |
| Indawo yokunyibilika | N / A |
| Imbonakalo | Umgubo omhlophe |
| Ukunyibilikisa | Inyibilikiswa emanzini, ngokulinganayo kwii-munlip ezinemineral |
| Uzinzo | I-hygroscopic ngokulula |
Xa kuthelekiswa ne-phosphorus ye-phosphorus yendabuko, i-lanthanum carbonate inezi zinto zilandelayo:
Akukho calcium kunye ne-aluminium, ukhuseleko oluphezulu: kuthintela umngcipheko we-hypercalcemia kunye netyhefu ye-aluminim, ngakumbi kwizigulana ezinonyango lwexesha elide.
Isiphumo sokuncitshiswa kwephosphorus phosphorus, i-phosphorus ebalulekileyo ye-phosqurus: i-lanthanum carbonate inokubopha ngempumelelo kwi-phosphorus kwi-phosphorus kwi-phosphorus kwi-phosphorus kwi-phosforbus kwi-PH ye-PH, kwaye ubuchule bayo bokubopha bunamandla kunoboya be-phosphorus.
I-gestrointerninal engaphantsi kwengqondo, ukuthotyelwa kwesigulana: I-Lanthanum Carbonate inambitheka kakuhle, kulula ukuba ithathe, inomsindo omncinci, kwaye izigulana zinokubambelela kunyango lwexesha elide.
Ubungqina boPhando lweKlinikhi: I-lanthanum carbonate yenza kakuhle
Izifundo ezininzi zeklinikhi ziqinisekisile ukusebenza nokhuseleko lwe-lanthanum carbonate kwizigulana zeCKD. Izifundo zibonise ukuba i-lantnjaum carbonate ayinaphantsi okanye ingaphezulu kakhulu kwi-phosphate yemveli ye-phosphate ekunciphiseni amanqanaba e-phosphorus ye-phosphorus, kwaye inokulawula ngokufanelekileyo izikhombisi ze-IPTAbolis. Ukongeza, ukhuseleko lonyango lwexesha elide nge-lanthanum carcelnate ilungile, kwaye akukho qokelelo olucacileyo lwe-lanthanum kunye neemeko ezinetyhefu zifunyenwe.
Unyango lomntu ngamnye: Khetha olona cwangciso lubalaseleyo lwesigulana
Nangona i-Lanthanum Carbonate ineenzuzo ezininzi, oko akuthethi ukuba inokutshintsha ngokupheleleyo izibophelelo zemveli zephosphate zemveli. Ichiza ngalinye linezinto eziboniswayo kunye nezicwangciso zonyango, kwaye isicwangciso sonyango kufuneka sibekwe ngokwemeko ethile yesigulana.
I-Lanthanum Carbonate ilungele ezi zigulana zilandelayo:
Izigulana ezinehypercalcemia okanye umngcipheko we hypercalcemia
Izigulana ezinobuchule obukhulu okanye umngcipheko wokulwa kwe-vascular
Izigulana ezinonyamezelo okanye ukusebenza kakuhle kwezinto zemveli ze-phosphate zemveli
Ii-phots phosphate zemveli zisenokusetyenziselwa ezi zigulana zilandelayo:
Izigulana ezineemeko zoqoqosho ezinqongopheleyo
Izigulana ezingahambelaniyo okanye zokunganyamezeli i-lanthanum carbonate
Ukujonga kwikamva: I-Lanthanum Carbonate inekamva eliqaqambileyo
Ngokwenza nzulu kophando lweklinikhi kunye nokuqokelelwa kwamava obukrelekrele, imeko ye-lanthanum carbonate kunyango lwe-hyperphosphatia kwizigulana ze-CKD ziya kuqhubeka ziphucuka. Kwixa elizayo, i-lanthansum carbonate kulindeleke ukuba ibe yi-phosphate yokuqala ye-phosphate ye-phosphate, izisa iindaba ezilungileyo kwizigulana ze-CKD.
Ixesha lasemva kwexesha: Mar-25-2025